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Image Search Results
Journal: Scientific reports
Article Title: Disordered metabolism in mice lacking irisin.
doi: 10.1038/s41598-020-74588-7
Figure Lengend Snippet: Figure 6. Increased bone resorption in irisin lacking mice. (A, B) Sections of the distal shaft of the femur were stained with osteoprotegerin (OPG) (1:60) and receptor activator of nuclear factor-kB ligand (RANKL) (1:80) antibodies. Positive (black arrows) osteoblasts are shown, 200×. (C) Representative images of the distal metaphyseal region of the femur, together with cell counts (osteoclasts) per bone perimeter (Bpm). Red arrows, tartrate-resistant acid phosphatase (TRAP)-positive osteoclasts, 100×, (NIS-Elements Viewer, v4.2.0; https:// www.downza.cn/soft/2751-21.html); (D) serum levels of osteocalcin TRAP (with three replicates). (Graphpad Prism, v7.0, https://www.xue51.com/soft/3932.html). Data are presented as the mean ± SEM (n = 15 per group). *P < 0.05, **P < 0.01 compared to the WT group.
Article Snippet: The enzyme-linked immunosorbent assay (ELISA) kit for osteocalcin (OCN) (E06917m), Alkaline Phosphatase (ALP) (E0200m), and
Techniques: Staining
Journal: Experimental and Therapeutic Medicine
Article Title: Efficacy of vitamin D plus calcium with/without alendronate on bone metabolism in immunologic thrombocytopenic purpura patients with steroid treatment: Nine-month results of a randomized, double-blinded, controlled trial
doi: 10.3892/etm.2019.7694
Figure Lengend Snippet: Impact of ALN on bone metabolism markers. (A-C) Bone formation markers (A) BAP, (B) P1NP and (C) osteocalcin, and (D and E) bone resorption markers (D) TRACP-5b and (E) CTX, were measured at baseline levels and after 1, 3, 6 and 9 months of treatment with CalD or CalD + ALN. *P<0.05, **P<0.01 and ***P<0.001 vs. baseline levels. ALN, alendronate; CalD, caltrate D; BAP, bone-specific alkaline phosphatase; P1NP, type 1 procollagen N-terminal propeptide; TRACP-5b, tartrate resistant acid phosphatase 5b; CTX, C-terminal telopeptides of type 1 collagen.
Article Snippet: Serum bone-specific alkaline phosphatase (cat. no. 48262; BAP; Access Ostase, Beckman Coulter, Inc., Brea, CA, USA), type 1 procollagen N-terminal propeptide (cat. no. E-EL-H0185c; P1NP; Elabscience Biotechnology Co., Ltd, Wuhan, China),
Techniques: